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TU Delft – Nucleation Kinetics of Organic Compounds

Last updated 897 days ago by Albert Verver


NL GUTS Group of Users of Technology for Separation in the Netherlands


20131203 TU Delft - Mr. Samir Kulkarni – Nucleation Kinetics of Organic Compounds

For many crystal products polymorphism is not desired. Control of polymorphism is difficult. At TUD the approach from the kinetics of nucleation aims at controlled nucleation to reduce polymorphism.

Experiments with nucleation of the same crystal compound in different solvents and by using different functional groups for heterogeneous nucleation made possible to steer crystal formation. Results of modeling and experiments showed good correspondence. The experiments resulted in a predictive tool. www.tudelft.nl


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